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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDPK1
All Species:
21.21
Human Site:
Y333
Identified Species:
38.89
UniProt:
O15530
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15530
NP_002604.1
556
63152
Y333
G
C
E
E
M
E
G
Y
G
P
L
K
A
H
P
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_537000
560
63701
Y337
G
C
E
E
M
G
G
Y
S
P
L
R
A
H
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z2A0
559
63740
Y336
G
C
E
E
M
E
G
Y
G
P
L
K
A
H
P
Rat
Rattus norvegicus
O55173
559
63591
Y336
G
C
E
E
M
E
G
Y
G
P
L
K
A
H
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518589
320
36424
V134
T
D
F
G
T
A
K
V
L
S
A
D
S
K
Q
Chicken
Gallus gallus
Q6U1I9
432
48872
K246
L
T
D
F
G
L
C
K
E
N
I
E
H
N
G
Frog
Xenopus laevis
Q6GPN6
434
49096
K248
L
T
D
F
G
L
C
K
E
N
I
E
P
N
G
Zebra Danio
Brachydanio rerio
Q7ZTW4
433
48964
K247
L
T
D
F
G
L
C
K
E
N
I
E
P
N
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W0V1
836
94060
Y562
A
Q
D
E
F
G
Y
Y
E
S
I
R
A
H
P
Honey Bee
Apis mellifera
XP_394208
537
61368
Y329
Q
D
E
H
G
A
G
Y
P
S
I
R
A
H
P
Nematode Worm
Caenorhab. elegans
Q9Y1J3
636
71898
H361
T
S
Q
E
L
M
A
H
K
F
F
E
N
V
D
Sea Urchin
Strong. purpuratus
XP_786576
539
61612
Y338
G
C
D
E
C
G
G
Y
P
A
L
K
A
H
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q12236
1081
121642
D791
D
L
Q
L
L
E
D
D
Y
R
I
E
G
G
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
93.3
N.A.
94.8
95.3
N.A.
52.1
28.6
28
27.5
N.A.
32.5
54.1
32.5
58
Protein Similarity:
100
N.A.
N.A.
95
N.A.
96.2
96.4
N.A.
54.6
44
43.8
43.3
N.A.
44.1
66.1
52.2
70.3
P-Site Identity:
100
N.A.
N.A.
80
N.A.
100
100
N.A.
0
0
0
0
N.A.
33.3
40
6.6
66.6
P-Site Similarity:
100
N.A.
N.A.
86.6
N.A.
100
100
N.A.
6.6
26.6
26.6
26.6
N.A.
53.3
53.3
33.3
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
23.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
35.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
16
8
0
0
8
8
0
54
0
0
% A
% Cys:
0
39
0
0
8
0
24
0
0
0
0
0
0
0
0
% C
% Asp:
8
16
39
0
0
0
8
8
0
0
0
8
0
0
16
% D
% Glu:
0
0
39
54
0
31
0
0
31
0
0
39
0
0
0
% E
% Phe:
0
0
8
24
8
0
0
0
0
8
8
0
0
0
0
% F
% Gly:
39
0
0
8
31
24
47
0
24
0
0
0
8
8
24
% G
% His:
0
0
0
8
0
0
0
8
0
0
0
0
8
54
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
47
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
8
24
8
0
0
31
0
8
0
% K
% Leu:
24
8
0
8
16
24
0
0
8
0
39
0
0
0
0
% L
% Met:
0
0
0
0
31
8
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
24
0
0
8
24
0
% N
% Pro:
0
0
0
0
0
0
0
0
16
31
0
0
16
0
54
% P
% Gln:
8
8
16
0
0
0
0
0
0
0
0
0
0
0
8
% Q
% Arg:
0
0
0
0
0
0
0
0
0
8
0
24
0
0
0
% R
% Ser:
0
8
0
0
0
0
0
0
8
24
0
0
8
0
0
% S
% Thr:
16
24
0
0
8
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
8
0
0
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
54
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _